DecodeMyBio turns the 23andMe or AncestryDNA file you already own into a pharmacogenomic read of how your body is likely to process common medications. Upload your raw data and it maps your variants against the guidelines clinicians use — CPIC, ClinVar, and the FDA's Table of Pharmacogenomic Biomarkers — and cites every source. You also get carrier/ClinVar findings, nutrigenomics, and an ask-your-DNA chat.
Two things make it different. You pay $59 once and own your decode for life — no subscription on a genome that never changes. And it's honest about its limits: when a gene like CYP2D6 can't be reliably read from a consumer array, it tells you so instead of inventing a result. The only ongoing piece is optional — add a new prescription and it re-checks it against your DNA and alerts you when guidance changes. Informational, not medical advice.
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founder of decodemybio.com
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5founder of decodemybio.com
Hey 👋 I'm the founder of DecodeMyBio. Years ago a lot of us spat in a tube, got an ancestry result, and let the raw DNA file rot in a Downloads folder. That file still holds something genuinely useful: how your body is likely to process common medications. I built DecodeMyBio to unlock that — you upload the 23andMe/AncestryDNA file you already own, and it reads your DNA against the same guidelines clinicians use (CPIC, ClinVar, the FDA's own biomarker table), citing every source. Two decisions I want to be upfront about. One: you pay $59 once and own your decode for life — no subscription. A static genome doesn't justify a monthly bill. Two: it tells you the truth about its own limits. When a gene like CYP2D6 simply can't be read from a consumer array, it says so instead of guessing — because a confident wrong answer about your medication is the worst thing it could do. The one thing that is ongoing: add a new prescription and it re-checks it against your DNA, and alerts you when guidance changes. That's the optional part. It's informational, not medical advice — always talk to your clinician. I'll be here all day, ask me anything. 🧬
What I respect most here is the honesty about limits — telling users when a gene like CYP2D6 can't be reliably read instead of inventing a result is rare and genuinely builds trust. Quick question: do you support raw files beyond 23andMe and AncestryDNA (MyHeritage, Nebula…), and how is the uploaded file handled privacy-wise after the decode?
founder of decodemybio.com
Thanks, the limits point is the part I most wanted to get right, so it's good to hear it lands. On files, yes: 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA and Living DNA, plus VCF files from whole-genome sequencing services, Nebula included. Uploads can be .txt, .csv, .zip or .vcf.gz, with no pre-processing needed. What a file can actually answer varies by source and chip version, and you get told which parts yours supports rather than having it glossed over. On privacy: your file and the results derived from it are encrypted in transit and at rest, and they are kept so your results stay available and can be re-checked when guidance changes, rather than wiped on a timer. They are visible only to you. Nothing is sold, and nothing is shared with insurers or employers. You can delete your genetic data whenever you want, from inside the app, without having to ask anyone.
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Hey this is realy cool,have a doubt from my side. So, do you support raw files beyond 23andMe?
founder of decodemybio.com
Thanks. Yes, beyond 23andMe we take AncestryDNA, MyHeritage, FamilyTreeDNA and Living DNA, plus VCF files from whole-genome sequencing services like Nebula. Formats are .txt, .csv, .zip and .vcf.gz, no pre-processing needed. Coverage does vary by source and chip version, so you are told what your particular file can and canot support instead of it being papered over.